abstract：:Administration of intravenous vancomycin has been associated with the development of linear IgA bullous disease (LABD). In contrast to the idiopathic variant, vancomycin-induced LABD (VILABD) appears to be more transient and to be associated with lower morbidity. The characteristics of this entity remain undefined. Ou...

journal_title：Medicine

authors： Nousari HC,Kimyai-Asadi A,Caeiro JP,Anhalt GJ

更新日期：1999-01-01 00:00:00

abstract：:Four patients with systemic autoimmune disorders, 3 of a serious nature, presented to 1 cardiologist over a 20-month span. In 3 of these cases, an HMG-CoA reductase inhibitor was presumably etiologic, while in the fourth case, the HMG-CoA reductase inhibitor might have unmasked the disorder. It would be useful to dete...

journal_title：Medicine

authors： Rudski L,Rabinovitch MA,Danoff D

更新日期：1998-11-01 00:00:00

abstract：:Idiopathic chronic eosinophilic pneumonia (CEP) is a rare disorder of unknown cause with nonspecific respiratory and systemic symptoms but rather characteristic peripheral alveolar infiltrates on imaging, developing mainly in women and in atopic subjects. The disorder is highly responsive to oral corticosteroid therap...

journal_title：Medicine

authors： Marchand E,Reynaud-Gaubert M,Lauque D,Durieu J,Tonnel AB,Cordier JF

更新日期：1998-09-01 00:00:00

abstract：:Bacteremic nocardiosis is reported rarely. We discuss 4 recent cases seen at our institution and 32 other cases described in the English literature. We found that patients with bacteremic nocardiosis were similar in presentation, risk factors, course, and therapeutic outcome to nonbacteremic patients with nocardiosis....

journal_title：Medicine

authors： Kontoyiannis DP,Ruoff K,Hooper DC

更新日期：1998-07-01 00:00:00

abstract：:Thirty-five patients with clinical features and histologically or microbiologically proven infection met predetermined stringent criteria for invasive aspergillosis over a 5-year period at our institution. Underlying conditions included hematologic malignancy, solid tumor, bone marrow and solid organ transplantation, ...

journal_title：Medicine

authors： Kaiser L,Huguenin T,Lew PD,Chapuis B,Pittet D

更新日期：1998-05-01 00:00:00

abstract：:This report describes a case of d-lactic acidosis observed by the authors and then reviews all case reports of d-lactic acidosis in the literature in order to define its clinical and biochemical features and pathogenetic mechanisms. The report also reviews the literature on metabolism of d-lactic acid in humans. The c...

journal_title：Medicine

authors： Uribarri J,Oh MS,Carroll HJ

更新日期：1998-03-01 00:00:00

abstract：:Susac syndrome is an occlusive arteriolar disease that provokes infarcts in the cochlea, retina, and brain of young subjects, mostly women. Its cause is unknown. Some infarcts may be asymptomatic and only revealed by ancillary investigation: 1) audiogram that shows bilateral sensorineural hearing loss predominating on...

journal_title：Medicine

authors： Papo T,Biousse V,Lehoang P,Fardeau C,N'Guyen N,Huong DL,Aumaitre O,Bousser MG,Godeau P,Piette JC

更新日期：1998-01-01 00:00:00

abstract：:In this paper we present a prospective evaluation of 100 patients with Group A Streptococcal (GAS) bacteremia evaluated in our hospital over a 10-year period. Sixty-two patients were intravenous drug users (IVDU); all but 1 of these had an obvious cutaneous portal of entry related to the injection of illicit drugs. Tw...

journal_title：Medicine

authors： Bernaldo de Quirós JC,Moreno S,Cercenado E,Diaz D,Berenguer J,Miralles P,Catalán P,Bouza E

更新日期：1997-07-01 00:00:00

abstract：:The aquaporins are a family of membrane channel proteins that serve as selective pores through which water crosses the plasma membranes of many human tissues and cell types. The sites where aquaporins are expressed implicate these proteins in renal water reabsorption, cerebrospinal fluid secretion and reabsorption, ge...

journal_title：Medicine

authors： Lee MD,King LS,Agre P

更新日期：1997-05-01 00:00:00

abstract：:Idiopathic acute eosinophilic pneumonia (AEP) is an acute febrile illness that may be mistaken for an infectious pneumonia. Patients are often young and otherwise healthy. Clues to considering this disorder in a differential diagnosis include the acuity and severity of the clinical presentation and an initial chest X-...

journal_title：Medicine

authors： Pope-Harman AL,Davis WB,Allen ED,Christoforidis AJ,Allen JN

更新日期：1996-11-01 00:00:00

abstract：:We carried out a prospective study of 530 patients older than 14 years of age with brucellosis. We describe the incidence and clinical features of the focal forms of the disease, analyzing some of the possible factors associated with their appearance. One hundred sixty-nine patients (31.9%) had a focal form or complic...

journal_title：Medicine

authors： Colmenero JD,Reguera JM,Martos F,Sánchez-De-Mora D,Delgado M,Causse M,Martín-Farfán A,Juárez C

更新日期：1996-07-01 00:00:00

abstract：:Three distinct disorders of calcium homeostasis can result from mutations in the gene encoding the human calcium-sensing receptors (CASR; MIM 145980). One form of autosomal dominant familial hypocalciuric hypercalcemia results from the heterozygous state of inactivating mutations in the CASR gene. Neonatal severe hype...

journal_title：Medicine

authors： Pollak MR,Seidman CE,Brown EM

更新日期：1996-05-01 00:00:00

abstract：:The occurrence and characteristics of remissions in patients with systematic lupus erythematosus (SLE) have not been determined. We therefore studied this in a cohort of 667 patients and found that 156 patients had achieved at least 1 period of 1 year or more of treatment-free clinical remission. This represents an in...

journal_title：Medicine

authors： Drenkard C,Villa AR,Garcia-Padilla C,Pérez-Vázquez ME,Alarcón-Segovia D

更新日期：1996-03-01 00:00:00

abstract：:The authors propose to encompass under the designation of "fasciitis-panniculitis syndromes" (FPS) a group of disorders characterized by induration of the skin due to chronic inflammation and fibrosis of the subcutaneous septa and muscular fascia. The prototype of the FPS is eosinophilic fasciitis. Thirty-two consecut...

journal_title：Medicine

authors： Naschitz JE,Boss JH,Misselevich I,Yeshurun D,Rosner I

更新日期：1996-01-01 00:00:00

abstract：:To assess the role of circulating immune complexes (CIC) in chronic hepatitis C virus (HCV) infection, the relative frequency of CIC was determined in 60 patients with chronic hepatitis C alone, 19 patients co-infected with hepatitis B and C, 15 asymptomatic HCV carriers, and 54 healthy controls. Levels of CIC were de...

journal_title：Medicine

authors： Tsai JF,Jeng JE,Chang WY,Ho MS,Lin ZY,Tsai JH

更新日期：1995-05-01 00:00:00

abstract：:We report 3 cases of systemic strongyloidiasis in HIV-infected individuals and review 11 additional cases reported in the English-language literature. Systemic strongloidiasis is a rare and potentially fatal complication of late-stage HIV disease. A combination of gastrointestinal and respiratory symptoms in an HIV-in...

journal_title：Medicine

authors： Celedon JC,Mathur-Wagh U,Fox J,Garcia R,Wiest PM

更新日期：1994-09-01 00:00:00

abstract：:Budd-Chiari syndrome (BCS) may not be as uncommon as was once believed. Our study has substantiated the existence of 2 major clinical forms. The acute syndrome is invariably associated with extensive blockage of the major hepatic veins, resulting in congestive liver cell necrosis. In a small, but significant, number o...

journal_title：Medicine

authors： Dilawari JB,Bambery P,Chawla Y,Kaur U,Bhusnurmath SR,Malhotra HS,Sood GK,Mitra SK,Khanna SK,Walia BS

更新日期：1994-01-01 00:00:00

abstract：:Brachfeld and Gorlin's revised concept of subaortic stenosis derived from their recognition that the large magnitudes of the pressure gradients were incompatible with the relatively mild anatomic lesions found at surgery in 3 of their patients, and the rapidity of their arterial pulse upstroke. They proposed that a gr...

journal_title：Medicine

authors： Criley JM,Siegel RJ

更新日期：1993-11-01 00:00:00

abstract：:We studied 121 patients with systemic lupus erythematosus (SLE), of whom 119 were complement typed. Both black and white patients with SLE were more likely than racially matched controls to have a C4A null allotype. Patients with homozygous C4A deficiency had less proteinuria than other patients (p = 0.02) and both ho...

journal_title：Medicine

authors： Petri M,Watson R,Winkelstein JA,McLean RH

更新日期：1993-07-01 00:00:00

abstract：:We present 6 cases of spontaneous hemothorax and comprehensively review the medical literature on this subject. We categorize the reported causes and offer a rational diagnostic approach to patients with nontraumatic hemothorax. We recommend specific treatments for specific etiologies, and emphasize the importance of ...

journal_title：Medicine

authors： Martinez FJ,Villanueva AG,Pickering R,Becker FS,Smith DR

更新日期：1992-11-01 00:00:00

abstract：:The annual number of cases of culture-proven extrapulmonary tuberculosis (TB) at our hospital increased from 47 cases in 1983 to 113 cases in 1988. At least 43% (199) of 464 consecutive patients with extrapulmonary TB during this 6-year period were infected with the human immunodeficiency virus (HIV); since HIV serolo...

journal_title：Medicine

authors： Shafer RW,Kim DS,Weiss JP,Quale JM

更新日期：1991-11-01 00:00:00

abstract：:Poikilothermia, the inability to maintain a constant core temperature independent of ambient temperature, markedly influences both the mental and physical function of affected patients; furthermore, prolonged hypothermia can induce numerous complications. To establish the pathophysiology of thermoregulation underlying...

journal_title：Medicine

authors： MacKenzie MA,Hermus AR,Wollersheim HC,Pieters GF,Smals AG,Binkhorst RA,Thien T,Kloppenborg PW

更新日期：1991-07-01 00:00:00

abstract：:More than a decade has passed since the introduction of the concept that inhibition of platelet function may be helpful in preventing the initiation of thrombus formation. Aspirin has been recognized as inhibiting normal platelet function and the mechanism has been clearly delineated. Legions of patients have been stu...

journal_title：Medicine

authors： Lekstrom JA,Bell WR

更新日期：1991-05-01 00:00:00

abstract：:Ataxia-telangiectasia is a syndrome with many facets, involving a progressive cerebellar ataxia, immunodeficiency, cancer susceptibility, radiosensitivity, defects in DNA repair/processing, chromosomal breakage and rearrangements, elevated serum alphafetoprotein, and premature aging. Ataxia-telangiectasia is an autoso...

journal_title：Medicine

authors： Gatti RA,Boder E,Vinters HV,Sparkes RS,Norman A,Lange K

更新日期：1991-03-01 00:00:00

abstract：:A small clinically distinct group of patients with widespread tissue granulomata are described. The principal presenting symptoms are malaise, fever, and weight loss, although a wide variety of complaints are documented. Pulmonary involvement is uncommon. The granulomata are noncaseating with a few multinucleate giant...

journal_title：Medicine

authors： Friedland JS,Weatherall DJ,Ledingham JG

更新日期：1990-11-01 00:00:00

abstract：:Mannitol is widely used to reduce intracranial pressure and is protective against ischemic and nephrotoxic acute renal failure. However, the capacity of this seemingly innocuous agent to produce acute renal failure is not well recognized. We report herein the clinical course of 8 cases of mannitol-induced acute renal ...

journal_title：Medicine

authors： Dorman HR,Sondheimer JH,Cadnapaphornchai P

更新日期：1990-05-01 00:00:00

abstract：:We describe the clinical characteristics and actuarial survival of a consecutive cohort of 41 patients with rheumatoid arthritis and clinical pericarditis who were seen at the Mayo Clinic between 1970 and 1987 and followed up until death or through 1987. The survivors were followed up for a median of 5.1 years. Approx...

journal_title：Medicine

authors： Hara KS,Ballard DJ,Ilstrup DM,Connolly DC,Vollertsen RS

更新日期：1990-03-01 00:00:00

abstract：:Research and management of XLH have concentrated on the disease in childhood, and the natural history and morbidity of XLH in adult life are thus poorly understood. We have studied 22 adults (6 men) with XLH to clarify these aspects of this most common inherited form of rickets and osteomalacia. Most study participant...

journal_title：Medicine

authors： Reid IR,Hardy DC,Murphy WA,Teitelbaum SL,Bergfeld MA,Whyte MP

更新日期：1989-11-01 00:00:00

abstract：:We present 2 cases of the Lemierre syndrome (also called postanginal septicemia), along with 36 other cases from a review of recent literature. A review of the literature during the preantibiotic era is also included. This disease is caused by an acute oropharyngeal infection with secondary thrombophlebitis of the int...

journal_title：Medicine

authors： Sinave CP,Hardy GJ,Fardy PW

更新日期：1989-03-01 00:00:00

abstract：:Human T lymphotropic virus type 1 (HTLV-I) is a retrovirus which is prevalent in southern Japan, the Caribbean Basin, and Africa. Recent seroprevalence studies in the United States suggest that there are about 50,000 infected individuals. The identification of 5 individuals with HTLV-I-associated leukemia/lymphoma ref...

journal_title：Medicine

authors： Ratner L,Poiesz BJ

更新日期：1988-11-01 00:00:00

abstract：:The enterococci, members of the group D streptococci and the predominant aerobic streptococci of the gastrointestinal and female genital tracts, have long been recognized as significant pathogens in infective endocarditis. Over the past 2 decades, enterococci have become increasingly important nosocomial pathogens, re...

journal_title：Medicine

authors： Maki DG,Agger WA

更新日期：1988-07-01 00:00:00

abstract：:Clinical, roentgenographic and pathologic findings in patients with chronic eosinophilic pneumonia, including 19 additional cases, have been reviewed and summarized. Most patients present with subacute respiratory and constitutional symptoms and have failed to respond to therapy for presumptive pneumonia. A previous h...

journal_title：Medicine

authors： Jederlinic PJ,Sicilian L,Gaensler EA

更新日期：1988-05-01 00:00:00

abstract：:The clinical and laboratory findings in 14 infants, 2 children and 42 adults with RTA-1 have been retrospectively analyzed and the patients classified as having the hereditary (14%), acquired (31%), or idiopathic (55%) form. In 7 of the 8 hereditary cases, RTA-1 appeared to be a complication of hereditary hypercalciur...

journal_title：Medicine

authors： Caruana RJ,Buckalew VM Jr

更新日期：1988-03-01 00:00:00

abstract：:While salmonellosis is often considered to affect primarily the gastrointestinal tract, infection at other sites may occur, producing characteristic clinical syndromes. We reviewed cases from our institutions and the literature on focal manifestations of salmonella infections. In the past, most extra-intestinal salmon...

journal_title：Medicine

authors： Cohen JI,Bartlett JA,Corey GR

更新日期：1987-09-01 00:00:00

abstract：:Cardiac myxoma is a true intracardiac neoplasm, which is histologically benign but which on occasion may exhibit behavior suggestive of a true malignancy. It is the most common form of primary cardiac tumor, accounting for 50% of such neoplasms. Seventy-five percent of myxomas are found in the left atrium, typically a...

journal_title：Medicine

authors： Markel ML,Waller BF,Armstrong WF

更新日期：1987-03-01 00:00:00

abstract：:Clinical features, findings of diagnostic studies, results of therapy, and prognostic factors were analyzed in 45 patients with brain abscesses. The number of patients diagnosed yearly has increased since CT scanning became available, but despite the enhanced sensitivity, the time from either onset of symptoms or hosp...

journal_title：Medicine

authors： Chun CH,Johnson JD,Hofstetter M,Raff MJ

更新日期：1986-11-01 00:00:00

abstract：:Abnormalities in the parathyroid hormone (PTH) gene as a cause of hypoparathyroidism were evaluated by linkage analysis with DNA polymorphisms adjacent to the PTH gene in 8 families in which members were affected with familial isolated hypoparathyroidism (FIH). We found that in none of the 23 affected individuals was ...

journal_title：Medicine

authors： Ahn TG,Antonarakis SE,Kronenberg HM,Igarashi T,Levine MA

更新日期：1986-03-01 00:00:00

abstract：:In a retrospective analysis of 40 hospitalized patients with the Guillain-Barré syndrome (GBS), we related the use and outcome of assisted ventilation to specific quantitative details of the neurologic illness. Two patients had an unusually prolonged course: they were ventilated for 374 and 396 days before successful ...

journal_title：Medicine

authors： Sunderrajan EV,Davenport J

更新日期：1985-09-01 00:00:00

abstract：:We present 11 patients with immunotactoid glomerulopathy, a new syndrome characterized clinically by proteinuria (11/11), microscopic hematuria (9/11) and hypertension (9/11). The patients consisted of six females and five males, aged 25 to 59 years (mean, 44.6). Proteinuria was the presenting feature and the reason f...

journal_title：Medicine

authors： Korbet SM,Schwartz MM,Rosenberg BF,Sibley RK,Lewis EJ

更新日期：1985-07-01 00:00:00

abstract：:We have compared the effect of therapy with immunosuppression alone to immunosuppression plus plasma exchange on the clinical course and rate of disappearance of antibody in 17 patients with anti-glomerular basement membrane (anti-GBM) antibody-induced renal disease. Patients receiving immunosuppression (n = 9) and th...

journal_title：Medicine

authors： Johnson JP,Moore J Jr,Austin HA 3rd,Balow JE,Antonovych TT,Wilson CB

更新日期：1985-07-01 00:00:00